Description
SS-31 Peptide (SS31 / SS 31): Comprehensive Research Overview

The compound commonly known as SS-31 peptide—also referenced as SS31 peptide, SS 31 peptide, and SS-31—has become one of the most discussed mitochondrial research peptides in modern scientific literature. Although it is not approved for human use and is offered strictly for laboratory and research applications, interest in SS-31 continues to grow due to its unique biochemical structure and its interactions with cellular components that have drawn attention in various pre-clinical experimental settings.
Today, SS-31 is frequently utilized by researchers exploring mitochondrial function, cellular stress responses, and peptide–lipid interactions. Pure Tested Peptides, a U.S.-based provider of research-grade compounds, offers what many researchers consider the purest, fully lab-tested SS-31 peptide for sale nationwide, ensuring consistency and reliability for controlled scientific study.
What Is SS-31 Peptide? Understanding SS31 and SS 31 in Research

Originally identified through peptide libraries focused on mitochondrial-targeting sequences, SS-31 peptide is categorized as a small, aromatic-cationic tetrapeptide. The compound has been studied for how it interacts with mitochondrial membranes, particularly cardiolipin-rich regions. Research teams studying biochemical pathways have shown that SS-31 is capable of penetrating the mitochondrial inner membrane, which has generated scientific interest in its potential to support research into oxidative stress, cellular energetics, and mitochondrial integrity.
Studies published in peer-reviewed journals have often highlighted how SS31 peptide may bind to specific lipids within mitochondria. This binding activity is of particular interest to laboratories investigating the structural biology of mitochondrial membranes. Because mitochondria are central to cellular energy production, understanding peptide–lipid interactions is a key area of ongoing academic exploration.
It is important to emphasize that all findings involving SS-31, SS 31 peptide, or SS-31 peptides exist solely within controlled research environments. These studies are non-clinical and pre-clinical, and SS-31 is not approved for therapeutic, diagnostic, or human applications of any kind.
Research Applications of SS31 Peptide (SS-31 Peptides for Sale)

Researchers have examined SS-31 across a range of laboratory settings, many of which involve mitochondrial biology. A considerable portion of published literature explores:
- SS31 in mitochondrial membrane interaction research — Scientists have investigated how SS-31 peptide binds to cardiolipin and how this binding may influence membrane stability under experimental conditions.
- Studies related to oxidative stress models — Numerous research teams use SS-31 in oxidative stress simulations to observe mitochondrial resilience, electron flow, and cellular load response.
- Evaluating mitochondrial structure and dynamics — Some laboratories utilize SS-31 as part of experiments aimed at understanding mitochondrial fission, fusion, and morphology under various forms of cellular stress.
Again, none of these studies indicate or suggest health effects, and no claims of biological outcomes in humans may be made. All investigations remain pre-clinical and are intended exclusively for better understanding cellular behavior at the mitochondrial level.
As scientific interest has expanded, so has the demand for SS-31 peptides for sale that meet strict purity and quality parameters. Researchers routinely emphasize that reliable data require consistent, contaminant-free, lab-tested materials—something Pure Tested Peptides has become known for within the research community.
Why Researchers Choose Pure Tested Peptides for SS-31 Peptide
When seeking SS-31 peptide for sale, research teams often focus on purity, laboratory verification, and stability. Pure Tested Peptides is recognized for offering SS-31 that meets each of these criteria. Each batch undergoes rigorous testing, including HPLC and mass-spectrometry validation, ensuring high levels of accuracy and reproducibility for experiments.
In a field where minor impurities can significantly affect experimental outcomes, dependable suppliers are essential. Pure Tested Peptides emphasizes transparent testing reports, U.S.-based manufacturing oversight, and strict handling procedures. This has led many laboratories to rely on Pure Tested Peptides as a leading source of SS31 peptide and related research compounds.
Every SS-31 product from Pure Tested Peptides is labeled for research use only. The compound is not intended for veterinary or human use under any circumstances and may not be ingested, injected, or used outside of controlled laboratory study.
How SS-31 (SS31 Peptide) Is Used in Research Settings
In laboratory environments, SS-31 is typically studied in controlled in vitro systems or pre-clinical models. Scientists may dissolve SS-31 in sterile solutions to evaluate its stability, structural characteristics, and interactions with mitochondrial lipids. Some laboratories also use fluorescent tagging or molecular imaging technologies to observe SS-31 peptide localization within cell membranes.
Research has indicated that SS-31’s small size and charge profile may promote rapid intracellular uptake. This characteristic is part of what makes the compound compelling for mitochondrial research, as it allows scientists to examine peptide trafficking and membrane targeting mechanisms.
However, even with rapidly growing interest, SS-31 peptide remains exclusively within the realm of scientific experimentation. No regulatory authority has approved SS-31 for human use, and Pure Tested Peptides reiterates that it is not sold as a supplement, therapy, or consumable of any kind.
SS-31 Peptide (SS 31 / SS31): Structural Features of Research Significance
Structural attributes of SS-31 have placed it at the center of numerous research discussions. The peptide’s aromatic ring and cationic character are believed to contribute to its strong affinity for cardiolipin. This characteristic may make SS-31 an ideal investigative tool for studies exploring membrane potential, lipid oxidation, and mitochondrial signaling pathways.
The compact nature of SS-31 peptide allows researchers to use it in high-accuracy studies involving molecular modeling and spectroscopic analysis. Nuclear magnetic resonance (NMR), crystallography, and other advanced imaging techniques are commonly employed to more clearly visualize how SS-31 behaves on a molecular level.
These attributes also make SS-31 a valuable standard for comparative peptide studies. When evaluating how different peptides interact with lipids, proteins, or mitochondrial structures, SS-31 is often selected as a reference standard due to the substantial amount of peer-reviewed research available on its molecular characteristics.
Buying SS-31 Peptide for Research: What to Look For
Because SS-31 peptides for sale must meet strict research standards, choosing the right supplier is essential. Researchers typically consider factors such as:
- Purity verification via HPLC, MS, or COA documentation
- U.S.-based production to ensure regulatory oversight
- Proper sterilization and handling during packaging
- Accurate labeling indicating research-use only
- Batch consistency for repeatable scientific results
Pure Tested Peptides is widely regarded as a premier provider in this category, offering some of the highest-purity SS-31 peptide available in the American research market. Their focus on quality control, batch transparency, and third-party testing makes them a trusted source for laboratories requiring dependable materials for mitochondrial studies.
Research-Use Only: Important Compliance Notes for SS-31 Peptide
All SS-31 peptide, SS31 peptide, and SS 31 peptide products supplied by Pure Tested Peptides are intended exclusively for laboratory research. Researchers must handle SS-31 according to all safety, storage, and compliance guidelines.
Key requirements include:
- SS-31 peptide may not be used in humans or animals.
- The compound must not be consumed, injected, inhaled, or applied topically.
- SS-31 must be stored properly to maintain stability for research accuracy.
- Researchers should follow institutional protocols for safe handling.
Pure Tested Peptides clearly labels all SS-31 products as “Research Use Only – Not for Human Use.” This ensures complete compliance and helps laboratories maintain the integrity of their research programs.
Why SS-31 Peptide Continues to Be a Focus of Scientific Interest
From its unique molecular profile to its highly targeted interactions with mitochondrial lipids, SS-31 remains a significant topic among researchers studying cellular energetics and mitochondrial biology. The growing library of academic papers referencing SS-31, SS 31, and SS31 peptide underscores its value as an investigative tool.
Whether used to explore oxidative stress pathways, membrane dynamics, or mitochondrial transport mechanisms, SS-31 provides a versatile and scientifically compelling platform for ongoing study. As more laboratories continue to expand their mitochondrial research programs, demand for SS-31 peptides for sale—especially those of the highest purity—continues to increase.
Pure Tested Peptides remains committed to supplying the purest SS-31 peptide in the USA, with verified laboratory testing, excellent batch consistency, and reliable nationwide delivery for research institutions, universities, and private laboratories.
Conclusion: SS-31 Peptide Research and Trusted Sourcing
SS-31 peptide, also known as SS31 or SS 31 peptide, plays a significant role in mitochondrial research and continues to be the subject of extensive pre-clinical investigation. With its unique structure and highly specific lipid-binding properties, SS-31 is an essential tool for laboratories studying mitochondrial biology.
For researchers seeking the purest SS-31 peptide for sale in the United States, Pure Tested Peptides provides unmatched quality, transparency, and laboratory-verified consistency. All SS-31 products are designated for research use only and are not approved for human consumption or application.
As interest in mitochondrial science grows, Pure Tested Peptides remains dedicated to supporting researchers with the highest-purity SS-31 available anywhere in the USA.

1. Mitochondrial Protection & Bioenergetics

SS-31 binds to the mitochondrial lipid cardiolipin, stabilizing cristae structure and enhancing oxidative phosphorylation, while dampening intrinsic apoptosis through inhibition of BAX activation.
2. Reduced Oxidative Stress & Age-Related Decline
SS-31 reverses age-related redox imbalance and restores mitochondrial quality in aged skeletal muscle—boosting endurance without increasing mitochondrial biogenesis.
PMC 6588449
In aged mice, it also restores cardiac diastolic function and reduces hypertrophy and ROS levels.
eLife 55513
3. Renal & Glomerular Health
In aged mice, SS-31 improves mitochondrial morphology, reduces glomerulosclerosis and cellular senescence, and preserves podocyte and endothelial integrity.
PubMed 28063595
It also shows promise in ameliorating acute kidney injury (AKI) and chronic renal disease by attenuating mitochondrial ROS and permeability transition.
PubMed 35707274
4. Neurovascular & Neuroprotective Effects
In aged mice, SS-31 restores neurovascular coupling by improving NO-mediated dilation, leading to enhanced memory and motor coordination.
PubMed 29405550
It also protects microglial cells from LPS-induced mitochondrial damage by suppressing Fis1-mediated mitochondrial fission.
PubMed 31582222
5. Musculoskeletal & Tendon Repair
SS-31 shows potential to enhance mitochondrial function in degenerative tendons, promoting repair in tendinopathy models.
PubMed 35862638
It also counters CANC-associated muscle wasting by preserving mitochondrial ATP levels and fiber integrity.
PubMed 33670497
6. Pain & Headache Relief via Mitochondrial Restoration
In a mouse headache model, SS-31 restored mitochondrial health in trigeminal neurons and reduced pain behaviors via activation of the SIRT3/PGC-1α pathway. If you are looking to Buy ss-31 peptide for sale consider the research behind it.
PubMed 37271805
References
- PubMed 34022923
- PubMed 32554501
- PMC 6588449
- eLife 55513
- PubMed 28063595
- PubMed 35707274
- PubMed 29405550
- PubMed 31582222
- PubMed 35862638
- PubMed 33670497
- PubMed 37271805
PLEASE NOTE THAT ALL PRODUCTS FEATURED HERE ARE INTENDED EXCLUSIVELY FOR RESEARCH AND DEVELOPMENT PURPOSES. THEY ARE NOT DESIGNED FOR ANY FORM OF HUMAN CONSUMPTION. THESE PRODUCTS HAVE NOT UNDERGONE EVALUATION BY THE U.S. FOOD AND DRUG ADMINISTRATION.
Taken together, these studies show SS‑31’s potential to mitigate neuroinflammation‑driven cognitive deficits and to restore mitochondrial redox homeostasis, thereby enhancing both brain function and physical endurance in preclinical models.











