Description
Epithalon Peptide: Research Overview & Structure
What Is Epithalon?
Epithalon (also called Epitalon or Epithalamin) is a synthetic tetrapeptide with the sequence Ala-Glu-Asp-Gly. It was originally derived from research on pineal peptides and has been studied in the context of cellular senescence and telomerase activation.
Chemical Structure
Epithalon is a short peptide composed of four amino acids:
- Ala โ Alanine
- Glu โ Glutamic acid
- Asp โ Aspartic acid
- Gly โ Glycine
Its small size contributes to stability and the ability to interact with regulatory pathways at the cellular level. It has been investigated as part of studies on aging biology and genome stability.
Mechanistic Insights from Research
Laboratory studies have reported that Epithalon may influence cellular mechanisms such as:
- Telomerase Activity: Research indicates Epithalon can stimulate telomerase in human somatic cells, potentially contributing to telomere elongation in vitro.
- Oxidative Stress Modulation: Some preclinical studies suggest effects on antioxidant systems and cellular homeostasis.
These findings remain preliminary and are primarily limited to in vitro and preclinical studies.
Selected Research References
- Khavinson V et al. Epithalamin induces telomerase activity in human somatic cells. PubMed 10833828.
- Anisimov VN et al. Pineal peptide Epithalon prolongs life span in rats. PubMed 11121901.
SEO Highlights
Target keywords: Epithalon peptide, epitalon, aging peptide, telomerase research, pineal peptides, chemical structure.
Meta description: Research-based overview of Epithalon peptide: chemical structure, telomerase activity, and published studies. Includes PubMed references. For research purposes only.
