Description
GLP-3 R Â Peptide
High-purity triple-receptor agonist for advanced metabolic research
Pricing & Sizes
Choose the vial size that fits your research needs. Discounts apply for bulk purchases.
| Vial Size | Price (USD) |
|---|---|
| 10 mg | $89.99 |
| 20 mg | $159.99 |
| 30 mg | $199.99 |
Key Features
- >99% purity confirmed by high-performance liquid chromatography (HPLC) and mass spectrometry.
- Triple agonist activity: selectively activates GLP-1, GIP and glucagon receptors for comprehensive metabolic research.
- Full Certificates of Analysis (COA) verifying peptide content, heavy metal absence and endotoxin levels (<0.25 EU).
- Third-party laboratory testing and lot-specific COA QR codes for full transparency.
- Lyophilized powder for superior stability; overfilled vials ensure stated yield.
- Ships from the USA via expedited shipping; free shipping on qualifying orders.
- For laboratory research use only – not for human consumption or diagnostic use.
Mechanism of Action
Retatrutide (GLP-3 R) is a 39-amino acid peptide engineered from the native glucose-dependent insulinotropic polypeptide (GIP) sequence. Strategic amino acid substitutions and a C-terminal fatty acid side chain extend its half-life and increase albumin binding. Retatrutide’s unique design allows it to simultaneously activate three metabolic hormone receptors:
- GLP-1 receptor – increases insulin secretion, suppresses glucagon release, slows gastric emptying and promotes satiety.
- GIP receptor – stimulates insulin secretion and enhances lipid metabolism.
- Glucagon receptor – increases energy expenditure and promotes fat oxidation.
By engaging all three receptors at once, retatrutide delivers synergistic effects on weight management, glycemic control and lipid metabolism.
Technical Specifications
| CAS Number | 2381089-83-2 |
| Molecular Formula | C221H342N46O68 |
| Molecular Weight | 4 731.35 g/mol |
| Sequence | Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-γ-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Appearance | White/off-white lyophilized powder |
| Storage | Store at 2–8 °C in a cool, dry place protected from light |
Research Applications
Retatrutide is an investigational peptide under active study for metabolic health. Published pre-clinical and early clinical research demonstrates profound reductions in body weight, liver fat and blood pressure while improving insulin sensitivity. Its triple agonism offers a powerful tool for researchers studying:
- Appetite regulation and energy expenditure pathways.
- Glucose tolerance and insulin secretion dynamics.
- Lipid metabolism and hepatic steatosis.
- Multi-hormone signalling interactions in obesity and type 2 diabetes models.
Note: This content is for educational purposes only. The peptide is supplied strictly for in-vitro research, and no therapeutic claims are made.
COA & Quality Assurance
Each vial of GLP-3 R is accompanied by a lot-specific Certificate of Analysis. Our testing protocols include:
-
HPLC chromatographic purity assessment (>99% pure).
-
LC–MS/MS verification of peptide identity and molecular weight.
-
Endotoxin testing to ensure levels below 0.25 EU/mL.
-
Heavy metal analysis confirming absence of cadmium, lead, arsenic and mercury.
Safety & Compliance
This peptide is intended for laboratory research use only. It is not a drug, food or cosmetic and must not be used on humans or animals. Researchers are responsible for handling and disposing of the compound in accordance with local regulations.
